【客户文章】 2019-Appl Microbiol Biotechnol-普洱茶减轻肥胖 — 美吉生物云-互动话题
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【客户文章】 2019-Appl Microbiol Biotechnol-普洱茶减轻肥胖

代谢组学专题微生态专题

普洱茶水提物和熟普洱茶水提物可减轻肥胖,改变饮食诱导肥胖大鼠盲肠菌群的组成和功能。

Y Xia,DH Tan,R Akbary,J Kong,R Seviour,YH Kong

Appl Microbiol Biotechnol, IF = 3.340

 

文献摘要:

The aim of this study was to investigate the effects of aqueous extracts of fermented (ripe) and non-fermented (raw) Pu-erh teas on the composition and function of the intestinal microbiota of rats with diet-induced obesity。 We conducted a comparative metagenomic and meta-proteomic investigation of the microbial communities in cecal samples taken from obese rats treated with or without extracts of raw or ripe Pu-erh teas。 By analyzing the composition and diversity of 16S rRNA amplicons and expression profiles of 814 distinct proteins, we found that despite differences in the chemical compositions of raw and ripe Pu-erh teas, administration of either tea at two doses (0。15- and 0。40-g/kg body weight) significantly (P < 0。05) increased microbial diversity and changed the composition of cecal microbiota by increasing the relative abundances of Firmicutes and decreasing those of Bacteroidetes。 Community metabolic processes, including sucrose metabolism, glycolysis, and syntheses of proteins, rRNAs, and antibiotics were significantly (P < 0。05) promoted or had a tendency (0。10 < P < 0。05) to be promoted due to the enrichment of relevant enzymes。 This study provides new evidence for the prebiotic effects of Pu-erh tea。

主要结果:


参考文献:

Yun Xia,Donghong Tan, et al. Aqueous raw and ripe Pu-erh tea extracts alleviate obesity and alter cecal microbiota composition and function in diet-induced obese rat. [J].Appl Microbiol Biotechnol. 2019, 297:124991103(4):1823-1835 Doi: 10.1007/s00253-018-09581-2



今天叫一 2019-11-04 15:55:18
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